Washington, D.C. 1895.
1 page on "War Department, Surgeon General's Office" letterhead, 10 x 8 inches, Washington, D.C., June 8, 1895. Written to Captain Frank A. Edwards, 1st Cavalry, a distinguished Army officer and veteran of the western Indian campaigns, diagnosing him with a form of gout but ruling out diabetes, in part: "...I have made a careful chemical and microscopical examination of the three samples of urine furnished by you. Briefly I may say that there is a large quantity of urate of soda and oxalate of lime in all of the samples...I do not find the least trace of sugar, and no albumen. I also had the chemist of the Museum to examine for sugar with a like result. I believe that the course of treatment recommended by Dr. Tyson of Philadelphia will be of great value to you, and would suggest in addition that you take considerable daily exercise..." Interestingly, Dr. Reed was incorrect in his recommendation and course of treatment for gout. His friend Dr. James Tyson, perhaps best known in the medical community for his pioneering use of the microscope, prescribed the drinking of lots of fluids as a remedy. This was concurred by Dr. Reed, who, in addition, prescribed "considerable daily exercise." It would take another three years before the German scientist and Nobel Prize recipient Dr. Emil Fischer proved that uric acid came from purines in foods and drinks and that gout could be treated through the strict alteration of diet. Dr. Walter Reed died at the age of 55, thus accounting for the fact that there are no signed letters on the autograph market today. Natural folds; very good(+) condition.
United States Major General and physician who in 1901 led the team that postulated and confirmed the theory that yellow fever is transmitted by a particular mosquito species.