16 pages. Slim 8vo, original gray printed wrappers., n.p., 1914. Reprinted from the Journal of Biological Chemistry, Vol. XVIII, No. 1, June 1914.
"In the practical application of proteins to nutrition Osborne and L.B. Mendel began their joint researches on 'synthetic diets,' and in 1914 made the great discovery that lysine and tryptophane are indispensable for rats." Castiglioni, p. 953.